Loyal | Blog

One step closer to a longevity drug: LOY-002 hits key FDA milestone. Read more →

Blog

Blog

Blog

Blog

Loyal’s Series C: $100M to advance the first longevity drug

02.11.26

Loyal’s Series C: $100M to advance the first longevity drug

Featured

02.11.26

One step closer to a dog longevity drug: What LOY-002’s safety milestone means to a practicing vet

01.13.26

One step closer to a dog longevity drug: What LOY-002’s safety milestone means to a practicing vet

Featured

For owners

For vets

01.13.26

Did you know you and your dog age similarly? Mapping canine aging at the molecular level

01.07.26

Did you know you and your dog age similarly? Mapping canine aging at the molecular level

Featured

Publication

01.07.26

The STAY study finishes enrollment: A big day for dog-kind!

07.14.25

The STAY study finishes enrollment: A big day for dog-kind!

STAY study

07.14.25

Inside Loyal: Meet the team

03.11.25

Inside Loyal: Meet the team

03.11.25

Breaking records: the STAY study enrolls 1,000 dogs

04.14.25

Breaking records: the STAY study enrolls 1,000 dogs

For owners

For vets

STAY study

04.14.25

Not just for big dogs! Our senior dog program receives preliminary FDA efficacy acceptance (RXE)

02.26.25

Not just for big dogs! Our senior dog program receives preliminary FDA efficacy acceptance (RXE)

Featured

For owners

02.26.25

Publication highlight: What lab values tell us about dogs’ frailty and quality of life

08.28.25

Publication highlight: What lab values tell us about dogs’ frailty and quality of life

For vets

08.28.25

What Loyal’s LOY-002 RXE milestone means: A practicing vet’s perspective

02.26.25

What Loyal’s LOY-002 RXE milestone means: A practicing vet’s perspective

Featured

For vets

02.26.25

New year, new dog! 5 essential health tips for your dog in 2025

01.08.25

New year, new dog! 5 essential health tips for your dog in 2025

Featured

For owners

01.08.25

6 tips for traveling with your (senior) dog this holiday season

11.21.24

6 tips for traveling with your (senior) dog this holiday season

For owners

11.21.24

A toast to 2024: Big steps forward in dog longevity

12.18.24

A toast to 2024: Big steps forward in dog longevity

12.18.24

What to include in senior dog wellness exams: 5 clinical assessments for vets

11.18.24

What to include in senior dog wellness exams: 5 clinical assessments for vets

For vets

11.18.24

How’s the STAY study going? Here’s an update from the vet who designed it.

10.09.24

How’s the STAY study going? Here’s an update from the vet who designed it.

STAY study

10.09.24

Great Danes and granddads: How 'one medicine' is redefining healthy longevity

09.17.24

Great Danes and granddads: How 'one medicine' is redefining healthy longevity

For owners

09.17.24

Drugs and dietary supplements for dogs: What’s the difference?

08.28.24

Drugs and dietary supplements for dogs: What’s the difference?

08.28.24

The science behind lifespan extension: Metabolic dysfunction

07.16.24

The science behind lifespan extension: Metabolic dysfunction

Featured

Metabolic health

07.16.24

Linda Rhodes joins the Loyal Board of Directors

07.01.24

Linda Rhodes joins the Loyal Board of Directors

07.01.24

Can science actually make your dog live longer? The Purina study

06.25.24

Can science actually make your dog live longer? The Purina study

Featured

For owners

For vets

06.25.24

What is FDA conditional approval?

04.16.24

What is FDA conditional approval?

Featured

04.16.24

Same drugs, different species: How the effects of drugs vary between dogs and humans

09.24.24

Same drugs, different species: How the effects of drugs vary between dogs and humans

For owners

09.24.24

$125M to extend dog lifespan

03.21.24

$125M to extend dog lifespan

03.21.24

Meet Boo — the first dog dosed in our LOY-002 pivotal study for extending healthy lifespan in dogs of nearly all sizes

02.01.24

Meet Boo — the first dog dosed in our LOY-002 pivotal study for extending healthy lifespan in dogs of nearly all sizes

STAY study

02.01.24

FDA Center for Veterinary Medicine agrees Loyal’s data supports reasonable expectation of effectiveness for large dog lifespan extension

11.28.23

FDA Center for Veterinary Medicine agrees Loyal’s data supports reasonable expectation of effectiveness for large dog lifespan extension

Featured

11.28.23

Fetch KC recap: the questions so burning, curious vets stand in line to ask them

10.24.23

Fetch KC recap: the questions so burning, curious vets stand in line to ask them

10.24.23

Announcing our partnership with Crinetics Pharmaceuticals

08.11.23

Announcing our partnership with Crinetics Pharmaceuticals

08.11.23

The power of big datasets

08.08.23

The power of big datasets

For owners

For vets

08.08.23

Approved drugs for veterinary patients are on a roll, y’all (why that’s got me in my feelings)

06.08.23

Approved drugs for veterinary patients are on a roll, y’all (why that’s got me in my feelings)

06.08.23

Our LOY-002 clinical pilot study is now fully enrolled

04.11.23

Our LOY-002 clinical pilot study is now fully enrolled

04.11.23

You and your dog share similarities in your blood: Exploring markers of aging

03.28.23

You and your dog share similarities in your blood: Exploring markers of aging

Publication

03.28.23

Vet education recap: Resources for canine geriatric medicine

03.17.23

Vet education recap: Resources for canine geriatric medicine

For vets

03.17.23

Loyal’s latest milestone: the first longevity clinical study design supported by the FDA

03.10.23

Loyal’s latest milestone: the first longevity clinical study design supported by the FDA

03.10.23

How scientists measure aging through Healthspan, frailty and quality of life

02.16.23

How scientists measure aging through Healthspan, frailty and quality of life

Publication

02.16.23

Blake Scholl joins the Loyal Board of Directors

02.15.23

Blake Scholl joins the Loyal Board of Directors

02.15.23

Why are modern dog breeds so different from one another?

12.09.22

Why are modern dog breeds so different from one another?

12.09.22

How old is your dog, really? Predicting age through methylation

11.30.22

How old is your dog, really? Predicting age through methylation

11.30.22

Ancestry & DNA: decipher the biology behind your dog’s family tree

11.10.22

Ancestry & DNA: decipher the biology behind your dog’s family tree

11.10.22

What is DNA methylation and how does it help us understand longevity?

10.25.22

What is DNA methylation and how does it help us understand longevity?

10.25.22

Your dog may be sharing bacteria with you. But that’s a good thing!

09.20.22

Your dog may be sharing bacteria with you. But that’s a good thing!

09.20.22

How to help your dog lose weight and improve their quality of life

09.13.22

How to help your dog lose weight and improve their quality of life

09.13.22

How movement and exercise in dogs promotes longevity and healthier aging

09.08.22

How movement and exercise in dogs promotes longevity and healthier aging

09.08.22

Why do big dogs have unusually short lifespans compared to small dogs?

09.01.22

Why do big dogs have unusually short lifespans compared to small dogs?

09.01.22

Signs of senior years: looking old, feeling old, and acting old

08.25.22

Signs of senior years: looking old, feeling old, and acting old

08.25.22

Clinical trials in the real world: One practitioner’s perspective

08.17.22

Clinical trials in the real world: One practitioner’s perspective

For vets

08.17.22

Dog enrichment activities: Healthy brains and happy dogs

08.16.22

Dog enrichment activities: Healthy brains and happy dogs

08.16.22

Obesity and epigenetics

04.14.22

Obesity and epigenetics

04.14.22

Healthspan: the healthy prime of life

02.23.22

Healthspan: the healthy prime of life

02.23.22

Should you zoom call your dog?

02.16.22

Should you zoom call your dog?

02.16.22

Yes, dogs really can read facial expressions

02.09.22

Yes, dogs really can read facial expressions

02.09.22

Talking to your dog?

02.02.22

Talking to your dog?

02.02.22

Dogs are great models for aging biology

01.26.22

Dogs are great models for aging biology

01.26.22

Is aging inevitable?

01.19.22

Is aging inevitable?

01.19.22

Can your dog catch your yawn?

01.12.22

Can your dog catch your yawn?

01.12.22

Why do dogs age?

01.05.22

Why do dogs age?

01.05.22

Aging and evolution

12.29.21

Aging and evolution

12.29.21

Two Loyal-nominated compounds selected for the National Institute on Aging Interventions Testing Program

08.26.21

Two Loyal-nominated compounds selected for the National Institute on Aging Interventions Testing Program

08.26.21

Quantifying the Aging Process: Loyal in-licenses mouse-canine-human homogeneous epigenetic clock from UCSD

08.02.21

Quantifying the Aging Process: Loyal in-licenses mouse-canine-human homogeneous epigenetic clock from UCSD

08.02.21

Categories

Aging thesis

Senior dog science

Big dog science

Developing drugs

Dog health

Loyal news

Tags

Featured

For owners

For vets

Metabolic health

Publication

STAY study