Give dogs more
healthy years

Join our STAY study to help dogs
live longer, healthier lives.

Age 12
Age 11
About Loyal
and our drug
At Loyal, we’re a clinical-stage veterinary medicine company developing drugs intended to extend the healthy lifespan of dogs.

We’ve launched the STAY study — a double-blinded, placebo-controlled study recruiting 1,000 senior dogs in partnership with 55 veterinary clinics across the country. This is our final effectiveness study for LOY-002 to support our submission for FDA approval.
Want to join
our study?
We’ll be opening enrollment at study sites across the country over the coming months. To find a site near you, consult the map below.
Study benefits
Receive free vet check-ups

Associated lab tests at no cost

Advance science for dogs everywhere
Does your dog qualify?
For dogs 10 years and older

Dogs must weigh 14 lb or more

Willing to commit to a multi-year study

Enrolling now
Coming Soon
Fully Enrolled
Find a study site near you
veterinary clinics
participating dogs
Meet Mickey — a STAY study participant. His owner, Andy, shared with us why they joined the STAY study:

“Over the years, I’ve had seven pets who needed to be put down — it’s part of life. Mickey is my eighth companion.

We’ve been at this clinic since 2008. They take care of my animals. I trust them. I trust Dr. Ramirez, especially. This study felt like a win-win.”

Age 12
The launch of the STAY study is a major step toward making LOY-002 available to dogs everywhere. This study is designed to provide essential safety and efficacy data to support our product development and FDA approval.
The largest study of its kind
The STAY study is being conducted by vet clinics spanning the United States, and will include more than 1,000 dogs. To our knowledge, no one in animal health has run such a diverse and long-running clinical trial.
Not all study participants will receive the drug — some will receive a placebo pill instead. This give us a “control” that allows us to identify the actual impact the drug is having compared with dogs who did not receive the drug.
This is the gold standard in safety and effectiveness testing — neither the study participants nor the investigators will know who is receiving the drug or a placebo. This prevents bias in the results.
Age 8
Developing new medications
Preclinical studies
Early efficacy studies in controlled laboratory environments — proofs of concept that the drug will have the desired effect
Pilot study
A smaller version of the full clinical study that helps us ensure our study is well designed to deliver the safety and effectiveness data we require
Companion dog clinical study
A large-scale nationwide study evaluating the drug’s safety and effectiveness in real-world veterinary settings with pets
FDA approval*
Working with the FDA to review manufacturing, safety, and effectiveness data, our goal is to get the drug approved so vets can prescribe it for your dog
*FDA approval not guaranteed
Thanks for your interest in this clinical trial. Your participation is an important step in getting innovative, safe, and effective medications approved for dogs.
Why should my dog and I participate?
What’s expected of participants?
Will my dog get the drug if they participate?
Will my dog live longer if they participate?
My dog isn’t 10 years old yet — are they eligible to enroll?
Is this study safe for my dog?
Who is Loyal?