Everything you need to know about study requirements and sites open for enrollment
Loyal’s latest milestone: the first longevity clinical study design supported by the FDA
At Loyal we’re developing the first FDA-approved drugs explicitly intended to extend lifespan and healthspan, and being first means charting new waters.
On the path to FDA approval, we must run a clinical trial that objectively and robustly demonstrates that our drug extends dogs’ healthy lifespan, and does so safely. Because no one has developed a dog — or human — longevity drug before, we are building the path to FDA approval largely from scratch.
Last week we learned from the FDA that Loyal received protocol concurrence for our companion dog longevity study — likely the first time the FDA has given their blessing to a longevity clinical trial. Our regulatory expert Karen Greenwood weighs in on what this means for Loyal, for the field of aging, and for dogs everywhere.
How scientists measure aging through Healthspan, frailty and quality of life
Our Healthspan study results have been published in GeroScience. Let’s dive into the results.
How old is your dog, really? Predicting age through methylation
We know biological samples can tell us about our dog’s health and breed ancestry, but is the saliva in your dog’s mouth enough to tell us your dog’s age and birthday? The answer is, in some ways, yes.
Why do big dogs have unusually short lifespans compared to small dogs?
Dogs come in an astounding range of shapes and sizes. Explore how genetic differences impact age and how Loyal is working on extending the lives and health of large dogs.
Clinical trials in the real world: One practitioner’s perspective
Why I’d love to see general practitioners participate in clinical research: 5 compelling reasons from a former GP